Veteran defender Darren Powell remains some way short of fitness. The 33-year-old has been out since injuring his knee at the start of February and has now also picked up a groin problem.
Striker Sam Baldock is also unavailable to Ince as he battles to recover from a knee injury so Aaron Wilbraham and Jermaine Easter will continue to start in attack.
Wilbraham has scored three goals in the last two games and will be looking for more as the Dons look for a first win over Southampton in their fourth meeting this season.
Source: Team Talk